Nilontinib induced keratosis pilaris atrophicans

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Nilotinib-Induced Keratosis Pilaris

Nilotinib is a second-generation Bcr-Abl tyrosine kinase inhibitor (TKI) that is approved for the treatment of imatinib-resistant chronic myeloid leukaemia expressing the Bcr-Abl mutation. Cutaneous adverse drug reactions occur more frequently in patients using this medication. We present a case of nilotinib-induced keratosis pilaris that did not have accompanying symptoms of alopecia or prurit...

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Nilotinib-induced Keratosis Pilaris Associated with Alopecia Areata and Eyebrow Thinning

Tyrosine kinase enzymes are an attractive target for anticancer therapies. Tyrosine kinase inhibitors (TKI) are well tolerated; somehow severe systemic side effects are rarely seen during treatment. Toxicities of skin and appendages may lead to poor compliance, psychosocial inconvenience, and drug interruption. Changes of the hair can arise following cures with TKI. Nilotinib, a second-generati...

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Treatment of keratosis pilaris with 810-nm diode laser: a randomized clinical trial.

IMPORTANCE Keratosis pilaris (KP) is a common skin disorder of follicular prominence and erythema that typically affects the proximal extremities, can be disfiguring, and is often resistant to treatment. Shorter-wavelength vascular lasers have been used to reduce the associated erythema but not the textural irregularity. OBJECTIVE To determine whether the longer-wavelength 810-nm diode laser ...

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ژورنال

عنوان ژورنال: Dermatology Online Journal

سال: 2016

ISSN: 1087-2108

DOI: 10.5070/d3228032159